It's crucial to get a good first drive on this hole. If you're left with too much distance to make up on the 2nd and 3rd shots, you're more likely to encounter the water hazard on the right closer to the pin.
Keep it low! The drop off and rough to the left of the pin can make a short, simple hole a lot more complicated. If you can hit the ground to the right of the pin it quite possible to get a nice little skip and slide to the green.
Don't let the water scare you! A RHBH shot with a stable/overstable disc will fade back provided you don't rail on it too much or apply off axis torque.
While RHBH throwers may be tempted to go right of the tree line, it's a bit of a crapshoot to do so. Between the thick upper branches and the proximity of the trunks to one another it can be tough to make it back through if you land in the wrong spot. Stick with a slow turnover shot to the left.
If you know rollers, this is the hole to use one. The ground is flat, the grass is kept short, there's plenty of room for error, and there are no roots or rocks to throw you off course. This is all assuming you can't just throw 500ft of course.