Honestly not being a smart ass, but the biggest thing here is to experiment. Like Von Drehle said, certain disc, and certain weights, will do certain things. It's just like any other throw, you don't really know how it works out till you go out and practice, or experiment.
I honestly suggest everyone goes out in their field practice routine and takes every single disc they "throw" or have "bagged." Throw Tomahawks, Thumbers, hyzer, Anhyzer, Back hand, front hand, upside down scooby snacks and twinkies..... Ok, I was thinking about food. But, seriously, you should even try backhand and forehand rollers too. Try a Zinger too, they're DELICIOUS!