Brychanus
* Ace Member *
I really like that program you outlined! Compartmentalizes form changes to when they should happen, and the in-season component has really nice tapering down of the heavier loading/more fatiguing as you go thru the week and towards game day.
Also love the Friday visualization work. It reminds me of the shakeout sessions sprinters do the day before meets.
That's super cool that you are a neuroscientist - I bet you'll be able to help me with a lot of the terminology and specific physiology. Totally understand where you are coming from as I was pretty general about how I said the CNS stuff.
I'm mainly referring to the depletion of neurotransmitters from synapses (in brain and spine) and whatever other stuff happens from repetitive forceful muscle contractions, but I'm sure there is a lot of other stuff going on that you know much more about.
A lot of my background with it just comes from tried and true empirical evidence from S&C coaches over the decades, personal experience, and also Andrew Huberman's resources on his podcast but I'd love to learn more about it since it's so impactful to what I'm trying to do with sports.
Something I am curious about, is when we are exhausted from more mentally dominant work and then push it in the weight room (and do whatever it takes to hit the target numbers), I always feel exponentially more fatigue/limited ability to produce mental and physical outcomes, as well as drastically increased need for sleep. Do you and your peers think there may be some or lots of overlap between the neural pathways used for purely mental and purely motor-related functions (such that those synapses are both getting depleted at similar times, etc) or is it just overall brain "exhaustion" that causes the inhibitions?
Thanks re: the feedback on my general summary up there. Maybe other people can let us know how their own methods work.
Huberman's a serious academic scientist (meaning he gets major funding and publishes regularly in places most people in neuroscience would like to) with core research in neuroopthamology and regenerative mechanisms in visual pathways, plus some focus on physiological stress responses (cortisol and related effects). He usually works with mice. I wouldn't pretend to know as much as him there. He sometimes dabbles in conditioned fear responses or other nonvisual systems in rodents.
What I think I know better and is one of the core areas of debate in cognitive (mental) vs. physical fatigue is about the mechanisms of action. For a while, people thought that cognitive fatigue functioned similarly to depletion hypotheses in other systems like ACh depletion in motor end plates, somewhat like the gas tank running dry temporarily. Fine idea at face value. There was a period of debate and studies, and long story short, those hypotheses haven't fared well. The physiological evidence at the neurotransmitter level and the behaviors don't square up. Worse, the subjective ("felt") and objective (performative) indicators of cognitive and motor fatigue also don't always line up. So even if there ends up being some legitimacy to part of that story, it cannot be the whole thing.
At the same time and closer to my world, there were other models emerging about how brains predict rewards and deploys brain circuits to manage tasks ("effort"). As opposed to strictly the neurotransmitter level, they function at a computational level. Basically, if your brain predicts that a behavior is going to be sufficiently rewarding, it mounts more resources to complete the task and feels less fatigued. In that model, fatigue is associated with subjective or objective signals, which is your brain basically opting out when insufficient rewards are expected. Example: if you've ever been through an acutely stressful moment in a meeting at work where the future seems a little grim and felt tired right afterward, then you know what I am talking about. Those models are incomplete and involve a little bit of fuzziness, but are showing signs of success. *
The cognitive-physical thing you're talking about gets more interesting and more complicated. IMO no one has it fully figured out, because we barely understand parts of each end of it. There's almost certainly something true to stress hormones causing inflammatory responses that are cued by events (like working on something stressful) throughout the day that tax the body or are chronically elevated in distressed persons. Relatedly, there is also evidence that the computational thing happens here too because it is computing that the body is taxed - that fatigue you feel is the brain computing "enough is enough" and telling you to shut it down for recovery. These ideas together explain (in part) why people who find their job low stress and highly rewarding to be more likely to anticipate further rewards and get better responses from physical activity the same days they work.
*Incidentally these models are one way to explain why some people like athletes continue to grind through very hard processes - their brain has computed that it will be very rewarding after a long period of delayed gratification (weeks/months/years). They also tend to anticipate and then find things like hard workouts more rewarding than the average person.